hrp0097p1-4 | Adrenals and HPA Axis | ESPE2023
Schulte Sandra
, Eberhardt Nora
, Roedig Thea
, Schreiner Felix
, Plamper Michaela
, Bartmann Peter
, Holterhus Paul-Martin
, Kulle Alexandra
, Gohlke Bettina
Objective: Although low birthweight (bw) and unfavourable intrauterine conditions have been associated with metabolic sequelae in later life, little is known about their impact on glucocorticoid metabolism. We studied monozygotic twins with intra-twin bw-differences from birth to adolescence to analyse the long-term impact of bw and catch-up growth on glucocorticoid metabolism.Methods: 46 monozygotic prepubertal twin-pai...